Travelling by train from Roma in Italy to Zurigo in Switzerland is easy. Usually you travel via Milan. It might be the case that you first have to buy a ticket for travelling inside Italy and then a second one for travelling from Italy to Switzerland.
Your travel route could be like that.1 Roma (Italia) - Zurigo (Svizzera)
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Trova un luogo in cui dormire. Prenotazione facile e sicura.